HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-Bromo-1,5-dimethyl-1H-pyrrole-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1,5-Dimethylpyrrole-2-carbonitrile | HCID 91812 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-Bromo-1,5-dimethyl-1H-pyrrole-2-carbonitrile | HCID 15396583 | — |
Reaction Steps
A solution of bromine (6.58 mL, 0.13 mol) in acetic acid (60 mL) is added dropwise, with the aid of a dropping funnel, to a solution of 1,5-dimethyl-1H-pyrrole-2-carbonitrile (15.0 g, 0.12 mol) in acetic acid (300 mL). The batch is stirred at ambient temperature for 24 hours. The reaction mixture is then poured into a beaker containing 300 mL of water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115159B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-b593c36de88645c58631da8ce0735ef7 |
| Source note | uspto-grants-2015_08 |