Hydrochloric Acid → HCID 117831295, compound

HRID 518936Notes

Reaction equation

HRID 518936 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([C:55]2[CH:56]=[C:57]3[CH2:63][CH2:62][N:61]([CH3:64])[C:58]3=[N:59][CH:60]=2)[C:9]([C:11]2[CH:12]=[C:13]([C:20]3[CH:25]=[CH:24][C:23]([O:26][CH2:27][C:28](=[O:35])[N:29]4[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]4)=[CH:22][C:21]=3[C:36]([N:38]3[C@H:47]([CH2:48][N:49]4[CH2:54][CH2:53][O:52][CH2:51][CH2:50]4)[CH2:46][C:45]4[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=4)[CH2:39]3)=[O:37])[N:14]3[C:19]=2[CH2:18][CH2:17][CH2:16][CH2:15]3)=[O:10])=[CH:4][CH:3]=1.[ClH:65]>C(#N)C>[ClH:65].[OH:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]([C:55]2[CH:56]=[C:57]3[CH2:63][CH2:62][N:61]([CH3:64])[C:58]3=[N:59][CH:60]=2)[C:9]([C:11]2[CH:12]=[C:13]([C:20]3[CH:25]=[CH:24][C:23]([O:26][CH2:27][C:28](=[O:35])[N:29]4[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]4)=[CH:22][C:21]=3[C:36]([N:38]3[C@H:47]([CH2:48][N:49]4[CH2:54][CH2:53][O:52][CH2:51][CH2:50]4)[CH2:46][C:45]4[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=4)[CH2:39]3)=[O:37])[N:14]3[C:19]=2[CH2:18][CH2:17][CH2:16][CH2:15]3)=[O:10])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 117831216HCID 117831216, compound

Product 1

HCID 117831295HCID 117831295, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The base obtained in Step G (0.60 g, 0.69 mmol) is dissolved in acetonitrile and then converted into salt form using 0.7 mL (0.7 mmol) of 1N HCl solution. The solution is filtered, frozen and then lyophilised to provide the title compound in the form of a powder.

Workup

  1. filtrationThe solution is filtered
  2. temperaturefrozen

Sources & evidence

ORD record
ord-4261a947f1a9487c916338656ca7fe80
Source dataset
uspto-grants-2015_08
Patent number
US09115159B2

Reaction notes

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