Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52037Generated: October 28, 2026

2-Bromoethyl methyl ether → 6-(2-Methoxyethylamino)-4-(3'-methylanilino)quinazoline

https://huagongshe.com/reaction/52037

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoethyl methyl etherHCID 80972—
Reactant153436-70-5HCID 10220590—
Product6-(2-Methoxyethylamino)-4-(3'-methylanilino)quinazolineHCID 1996316220%

Reaction Steps

Using an analogous procedure to that described in Example 16, 6-amino-4-(3'-methylanilino)quinazoline was reacted with 2-bromoethyl methyl ether to give 6-(2-methoxyethylamino)-4-(3'-methylanilino)quinazoline in 20% yield, m.p. 163°-167° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616582
Source datasetuspto-grants-1997_04
ORD IDord-ff474c5ac3884f1a91b5ea1dfd3920fe
Source noteuspto-grants-1997_04