HCID 11118994, compound → HCID 15647195, compound

HRID 520374Notes

Reaction equation

HRID 520374 reaction equation
[O:1]=[C:2]1[CH:9]=[C:8]2[CH:4]([CH2:5][C:6]([C:15]([O:17][CH2:18][CH3:19])=[O:16])([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH2:7]2)[CH2:3]1>CCO.[Pd]>[O:1]=[C:2]1[CH2:3][CH:4]2[CH:8]([CH2:7][C:6]([C:10]([O:12][CH2:13][CH3:14])=[O:11])([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:5]2)[CH2:9]1

Participants

4

Reactant 1

HCID 11118994HCID 11118994, compound

Product 1

HCID 15647195HCID 15647195, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A stirred suspension of diethyl 5-oxo-3,3a,4,5-tetrahydropentalene-2,2(1H)-dicarboxylate (322 mg, 1.209 mmol) and 10% Pd—C (129 mg, 0.121 mmol) in EtOH (40 mL) was hydrogenated under balloon pressure overnight. The suspension was filtered and the filtrate was evaporated to dryness to afford diethyl 5-oxohexahydropentalene-2,2(1H)-dicarboxylate as a clear oil.

Workup

  1. customwas hydrogenated under balloon pressure overnight
  2. filtrationThe suspension was filtered
  3. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-2071b0e097c243a99b537e066820e0dc
Source dataset
uspto-grants-2016_05
Patent number
US09326973B2

Reaction notes

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