Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → HCID 86660237, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Tert-butyl 4-(morpholinomethyl)thiazol-2-ylcarbamate | HCID 58154672 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 86660237 | HCID 86660237 | 100% |
반응 단계
Tert-butyl 4-(morpholinomethyl)thiazol-2-ylcarbamate 90 (1.88 g, 6.28 mmol) was treated with 20 mL of 25% trifluoroacetic acid in CH2Cl2 for 18 h at room temperature. After all the solvent had been removed by concentrating and drying under high vacuum, the resulting residue was treated with a mixture of pentane/EtOAc to afford 91 (1.96 g, 100% yield) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09326986B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-7b49e0f97b4b4b0fb5a69cde5d0a513a |
| 출처 메모 | uspto-grants-2016_05 |