HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 520655Generated: October 31, 2026
Hydrochloric Acid → HCID 53233431, compound
https://huagongshe.com/reaction/520655
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 68226428 | HCID 68226428 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 53233431 | HCID 53233431 | — |
Reaction Steps
A solution of N-{1-(phenylsulfonyl)-6-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-indazol-4-yl}-2-furancarboxamide (80 mg) and 2M sodium hydroxide (2 ml) in IPA (4 ml) was stirred for 18 h at RT. The solution was heated at 70° C. for 1.5 h. The solution was cooled, neutralized with 2M HCl (aq) (2 ml) and purged with nitrogen to remove the IPA. The resulting solid was collected by filtration and dried in vacuo at 50° C. to give title compound, 30 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09326987B2 |
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| Source dataset | uspto-grants-2016_05 |
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| ORD ID | ord-2bfe53c5b13542378e7aebc0e6562ace |
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| Source note | uspto-grants-2016_05 |
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