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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 520795Generated: October 29, 2026

1-Ethynyl-3-fluorobenzene → HCID 90031129, compound

https://huagongshe.com/reaction/520795

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-3-fluorobenzeneHCID 520218—
ReactantHCID 90031855HCID 90031855—
ProductHCID 90031129HCID 9003112996%

Reaction Steps

The title compound was prepared in accordance with the general method of Example 1, step 7 using (3aR,6aR)-1-(5-iodopyridin-2-yl)hexahydro-cyclopenta[b]pyrrol-2(1H)-one (107 mg, 0.326 mmol) (Example 1, step 6) and 1-ethynyl-3-fluorobenzene to yield 100 mg (96%) of the title compound as a viscous yellow oil; MS: m/e=321.2 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328090B2
Source datasetuspto-grants-2016_05
ORD IDord-ee7bb520f7d3424b82d3c59c40d865c8
Source noteuspto-grants-2016_05