反应详情

In a 1-L Erlenmeyer flask, 25 g (100 mmol) of triphenylamine, 18 g (100 mmol) of N-bromosuccinimide, and 400 mL of ethyl acetate were put and stirred at room temperature in air for 24 hours. After the reaction, the reaction solution was washed twice with a saturated aqueous solution of sodium carbonate to separate into an aqueous layer and an organic layer. The aqueous layer was extracted twice with ethyl acetate and washed with saturated saline together with the organic layer. After the organic layer was dried with magnesium sulfate, natural filtration and enrichment was performed, and the resulting white solid was recrystallized with ethyl acetate and hexane, whereby 22 g of a white powder solid of 4-bromotriphenylamine was obtained at a yield of 66%.

1. customAfter the reaction
2. washthe reaction solution was washed twice with a saturated aqueous solution of sodium carbonate
3. customto separate into an aqueous layer
4. extractionThe aqueous layer was extracted twice with ethyl acetate
5. washwashed with saturated saline together with the organic layer
6. dry with materialAfter the organic layer was dried with magnesium sulfate, natural filtration and enrichment
7. customthe resulting white solid was recrystallized with ethyl acetate and hexane, whereby 22 g of a white powder solid of 4-bromotriphenylamine
8. customwas obtained at a yield of 66%