5-Chloro-2-(methylthio)aniline → HCID 57378991, compound

HRID 520920Notes

Reaction equation

HRID 520920 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH2:8])[CH:7]=1.[CH3:11][C:12]1[O:16][C:15]([S:17](Cl)(=[O:19])=[O:18])=[CH:14][CH:13]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH:8][S:17]([C:15]2[O:16][C:12]([CH3:11])=[CH:13][CH:14]=2)(=[O:19])=[O:18])[CH:7]=1

Participants

3

Reactant 2

HCID 27945775-Chloro-2-(methylthio)anilineHCID 178643615-Methylfuran-2-sulfonyl chloride

Product 1

HCID 57378991HCID 57378991, compoundYield 61.2%

Procedure

Following General Procedure B, the title compound (212 mg, 48%) was prepared from 5-chloro-2-methylsulfanyl-phenylamine (189 mg, 1.09 mmol) and 5-methyl-furan-2-sulfonyl chloride (250 mg, 1.38 mmol).

Sources & evidence

ORD record
ord-37e3329a8466493ea98d31883409dba5
Source dataset
uspto-grants-2016_05
Patent number
US09328067B2

Reaction notes

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