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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52101Generated: October 25, 2026

Acetic Anhydride → N-[5-(4-Piperidinomethyl-2-pyridyloxy)pentyl]-2-(2-acetoxyethylthio)acetamide

https://huagongshe.com/reaction/52101

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantN-[5-(4-Piperidinomethyl-2-pyridyloxy)pentyl]-2-(2-hydroxyethylthio)acetamideHCID 19962903—
ProductN-[5-(4-Piperidinomethyl-2-pyridyloxy)pentyl]-2-(2-acetoxyethylthio)acetamideHCID 1996295990%

Reaction Steps

Following a procedure similar to that described in Example 67(c), but using N-[5-(4-piperidinomethyl-2-pyridyloxy)pentyl]-2-(2-hydroxyethylthio)acetamide [prepared as described in step (a) above] and acetic anhydride as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 90% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616579
Source datasetuspto-grants-1997_04
ORD IDord-2e06c20db61040b698673f159290e624
Source noteuspto-grants-1997_04