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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521469Generated: October 30, 2026

2-(4-Methoxy-3-nitro-benzoylamino)-indane-2-carboxylic acid methyl ester → HCID 67076603, compound

https://huagongshe.com/reaction/521469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Methoxy-3-nitro-benzoylamino)-indane-2-carboxylic acid methyl esterHCID 67076671—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 67076603HCID 6707660396.2%

Reaction Steps

The compound of step 1 (0.43 g, 1.16 mmol) was dissolved in methanol (30 ml), 10% palladium on charcoal (200 mg) was added, and the flask flushed with argon. A balloon filled with hydrogen was connected, and the mixture was stirred at room temperature overnight. The balloon was removed, the flask flushed with argon, the catalyst filtered off over Celite, and the filtrate was evaporated in vacuo to give 0.38 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328071B2
Source datasetuspto-grants-2016_05
ORD IDord-a8a77da5c8524511a60ee7724c3dcb4d
Source noteuspto-grants-2016_05