HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride → HCID 67076726, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride | HCID 45074056 | — |
| Reactant | Methyl 5-bromo-6-methoxypyridine-3-carboxylate | HCID 46311221 | — |
| Product | HCID 67076726 | HCID 67076726 | — |
Reaction Steps
5-Bromo-6-methoxy-nicotinic acid methyl ester (W. J. Thompson and J. Gaudino, J. Org. Chem. 49 (1984), 5237-5243) (2.00 g, 8.13 mmol) was hydrolyzed in analogy to example 2. The obtained acid was reacted with 2-amino-indane-2-carboxylic acid methyl ester hydrochloride in analogy to step 2 of example 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328071B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-e51061dfa85b486786ee72748256699a |
| Source note | uspto-grants-2016_05 |