HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride → 2-[4-Methoxy-3-(2-methyl-benzoyl)-benzoylamino]-indane-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride | HCID 45074056 | — |
| Reactant | 4-Methoxy-3-(2-methyl-benzoyl)-benzoic acid methyl ester | HCID 67076629 | — |
| Product | 2-[4-Methoxy-3-(2-methyl-benzoyl)-benzoylamino]-indane-2-carboxylic acid | HCID 67076464 | — |
Reaction Steps
The compound of step 1 was hydrolyzed in analogy to example 2 and the obtained acid reacted with 2-amino-indane-2-carboxylic acid methyl ester hydrochloride in analogy to step 2 of example 13. The obtained ester was hydrolyzed in analogy to example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328071B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-86c52ae806c443fc922067c1747725c5 |
| Source note | uspto-grants-2016_05 |