HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-(6'-(benzo[d]thiazol-2-yl)-3,3'-bipyridin-6-yl)-N,N-diphenylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-(5-Bromopyridin-2-yl)benzo[d]thiazole | HCID 66799761 | — |
| Reactant | N,N-diphenyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)aniline | HCID 66801665 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 4-(6'-(benzo[d]thiazol-2-yl)-3,3'-bipyridin-6-yl)-N,N-diphenylaniline | HCID 56943732 | 81% |
Reaction Steps
Following the procedure for 3, 2 (0.521 g, 1.16 mmol), 9 (0.338 g, 1.16 mmol), tetrakis(triphenylphosphine)palladium(0) (67.1 mg, 58.1 μmol), Na2CO3 (1.59 g, 15.0 mmol), H2O (15 mL) and THF (25 mL) yielded 10 (0.50 g, 81% yield) as a bright yellow solid after flash chromatography (SiO2, 100% CH2Cl2 to 99:1 CH2Cl2—CH3OH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09328086B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-94f025b8d0034f5da46fe3601cf1e3f1 |
| Source note | uspto-grants-2016_05 |