3-Bromo-1,1,1-trifluoro-2-propanone → HCID 118035057, compound

Participants

Reaction Steps

A mixture of 1.91 g of 3-bromo-1,1,1-trifluoropropan-2-one and 5 ml of DME was added to a mixture of 1.74 g of 2-amino-5-bromopyrimidine and 15 ml of DME, and the mixture was stirred at room temperature for 1 day. The precipitated solid was taken by filtration, washed with 10 ml of DME, and dried to obtain 1.02 g of 6-bromo-2-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyrimidin-2-ol hydrobromide.

Provenance & Evidence