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3-Fluoropyridine-4-boronic acid → 2-(3-Fluoropyridin-4-yl)thiazole-4-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Fluoropyridine-4-boronic acid | HCID 2779353 | — |
| 反応物 | 2-(2,6-Difluoro-4-methoxyphenyl)thiazole-4-carboxylic acid | HCID 83410043 | — |
| 生成物 | 2-(3-Fluoropyridin-4-yl)thiazole-4-carboxylic acid | HCID 81749424 | — |
反応手順
Following the procedure of Intermediate 104, replacing 2,6-difluoro-4-methoxyphenylboronic acid with (3-fluoropyridin-4-yl)boronic acid gave the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09328106B2 |
| 出典データセット | uspto-grants-2016_05 |
| ORD ID | ord-e5be20fd30e944baa9986e59b6a78423 |
| 出典メモ | uspto-grants-2016_05 |