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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 521903Generated: October 26, 2026

(2,5-Difluorophenyl)boronic acid → 2-(2,5-Difluorophenyl)thiazole-4-carboxylic acid

https://huagongshe.com/reaction/521903

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2,5-Difluorophenyl)boronic acidHCID 2734335—
Reactant2-(2,6-Difluoro-4-methoxyphenyl)thiazole-4-carboxylic acidHCID 83410043—
Product2-(2,5-Difluorophenyl)thiazole-4-carboxylic acidHCID 63663588—

Reaction Steps

Following the procedure of Intermediate 104, replacing 2,6-difluoro-4-methoxyphenylboronic acid with (2,5-difluorophenyl)boronic acid gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328106B2
Source datasetuspto-grants-2016_05
ORD IDord-1d08c089e14648eb91b770a3cf99863e
Source noteuspto-grants-2016_05