反应详情

A mixture of 10 g compound (3), paraformaldehyde 1.6 g and dimethylamine chloride 4 g in 400 ml benzene was refluxed with stirring for 10 hours. After cooling to room temperature, the mixture was filtered by suction, a solid was obtained. The solid obtained was recrystallized from absolute ethanol, and 13.8 g of (4) was obtained as a white powder, mp 182°-183° C., yield 84%.

1. temperaturewas refluxed
2. filtrationthe mixture was filtered by suction
3. customa solid was obtained
4. customThe solid obtained
5. customwas recrystallized from absolute ethanol