HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 54189099, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | HCID 22328163 | HCID 22328163 | — |
| Reactant | 5-(4-Chlorobenzoyl)-1, 2-dihydro-1-pyrrolizinone | HCID 54199234 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 54189099 | HCID 54189099 | 113.1% |
Reaction Steps
A mixture of 10 g compound (3), paraformaldehyde 1.6 g and dimethylamine chloride 4 g in 400 ml benzene was refluxed with stirring for 10 hours. After cooling to room temperature, the mixture was filtered by suction, a solid was obtained. The solid obtained was recrystallized from absolute ethanol, and 13.8 g of (4) was obtained as a white powder, mp 182°-183° C., yield 84%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616604 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-7e2ebfc228f3430cb11aef0313acb617 |
| Source note | uspto-grants-1997_04 |