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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 522089Generated: October 30, 2026

(2R)-4-(Phenylmethyl)-2-morpholinemethanamine → (S)-5-(2-chloro-5-(3-fluoropyridin-2-yl)benzamido)-N-(morpholin-2-ylmethyl)-1-phenyl-1H-pyrazole-3-carboxamide

https://huagongshe.com/reaction/522089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-4-(Phenylmethyl)-2-morpholinemethanamineHCID 6932056—
Reactant5-(2-chloro-5-(3-fluoropyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylic acidHCID 118497109—
Product(S)-5-(2-chloro-5-(3-fluoropyridin-2-yl)benzamido)-N-(morpholin-2-ylmethyl)-1-phenyl-1H-pyrazole-3-carboxamideHCID 118497009—

Reaction Steps

The title compound was prepared according to the method described for Example 52 using 5-(2-chloro-5-(3-fluoropyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylic acid (Example 105) and (R)-(4-benzylmorpholin-2-yl)methanamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09328096B2
Source datasetuspto-grants-2016_05
ORD IDord-58932558be1a49448b7bff35505a0105
Source noteuspto-grants-2016_05