Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 118274112 | HCID 118274112 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 118274259 | HCID 118274259 | — |
Reaction Steps
To a solution of Example 41D (2.0 g, 3.75 mmol) in dioxane (30 mL) was added 1M aqueous sodium hydroxide (15 mL, 15 mmol) and the mixture was stirred at 50° C. overnight. Water was added and the precipitate was filtered, washed with water and hexanes and dried in vacuo to afford the title compound. LC-MS: 380 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09328112B2 |
|---|
| Source dataset | uspto-grants-2016_05 |
|---|
| ORD ID | ord-511f702bc6f648cb8d40dd08187981f7 |
|---|
| Source note | uspto-grants-2016_05 |
|---|
