HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N'-Dimethylethylenediamine → N-(4-cyanophenyl)-N-(4-(trimethylsilyl)phenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N'-Dimethylethylenediamine | HCID 8070 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Reactant | HCID 605997 | HCID 605997 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | N-(4-cyanophenyl)-N-(4-(trimethylsilyl)phenyl)acetamide | HCID 58536159 | — |
Reaction Steps
Under a flow of argon, in a 1 L-recovery flask, 27 g of N-(4-(trimethylsilyl)phenyl)acetamide, 30 g of 4-bromobenzonitrile, 6.3 g of copper (I) iodide, 45.6 g of potassium carbonate, and 412 mL of xylene were placed. After stirring, 7.1 mL of N,N′-dimethylethylenediamine was added. The resultant was heated and stirred at reflux for 18 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09331285B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-7cbec13858e745bbbf8209935a0bd2df |
| Source note | uspto-grants-2016_05 |