HRID522694
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
To a solution of tert-butyl 4-(5-(1-phenylcyclopropyl)pyrimidin-2-yl)piperazine-1-carboxylate (30 mg, 0.08 mmol) in dioxane (2 mL) was added 4 M HCl-dioxane (2 mL). The reaction mixture was stirred at room temperature overnight and then concentrated to afford crude 5-(1-phenylcyclopropyl)-2-(piperazin-1-yl)pyrimidin. MS (ES+) C17H20N4 requires: 280, found: 281 [M+H]+.
WORKUP
后处理
- concentrationconcentrated