HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 118676249, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Ethyl oxoacetate | HCID 70211 | — |
| Reactant | 3,4-Difluoroaniline | HCID 77469 | — |
| Product | HCID 118676249 | HCID 118676249 | — |
Reaction Steps
To a stirred solution of 2.0 g (15 mmol) of 3,4-difluoroaniline in methanol is added 4.0 g (39 mmol) of ethyl 2-oxoacetate. After stirring for 14 h, the mixture is concentrated to provide 3.7 g of I-03a that is used directly without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09334285B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-addf927a9751466e910a8425d896bb2a |
| Source note | uspto-grants-2016_05 |