3-(3-Ethoxy-4-nitrophenyl)-4-methyl-4H-1,2,4-triazole → 2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)aniline

HRID 523089Notes

Reaction equation

HRID 523089 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:13]2[N:17]([CH3:18])[CH:16]=[N:15][N:14]=2)[CH:7]=[CH:8][C:9]=1[N+:10]([O-])=O)[CH3:2]>CCOC(C)=O.CCO>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:13]2[N:17]([CH3:18])[CH:16]=[N:15][N:14]=2)[CH:7]=[CH:8][C:9]=1[NH2:10])[CH3:2]

Participants

4

Reactant 1

HCID 899956773-(3-Ethoxy-4-nitrophenyl)-4-methyl-4H-1,2,4-triazole

Product 1

HCID 899956322-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)aniline

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared according to the method described for Preparation 107 using 3-(3-Ethoxy-4-nitrophenyl)-4-methyl-4H-1,2,4-triazole (Preparation 116) in EtOAc and EtOH (1:8 v:v).

Sources & evidence

ORD record
ord-f35e0841564844e4be4e1850f274898a
Source dataset
uspto-grants-2016_05
Patent number
US09334286B2

Reaction notes

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