HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-D-phenylalanine → HCID 178445950, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-D-phenylalanine | HCID 637610 | — |
| Reactant | (2R)-1-((9H-fluoren-9-ylmethoxy)carbonyl)pyrrolidine-2-carboxylic acid | HCID 688136 | — |
| Reactant | (2R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid | HCID 978332 | — |
| Reactant | (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid | HCID 2756111 | — |
| Reactant | HCID 178427571 | HCID 178427571 | — |
| Product | HCID 178445950 | HCID 178445950 | — |
Reaction Steps
The compound was prepared according to the procedure described in the synthesis of compound (1). The amino acid derivatives used were Boc-D-Phe-OH, Fmoc-D-Phe-OH, Fmoc-D-Nle-OH, Fmoc-D-Arg(Pbf)-OH, and Fmoc-D-Pro-OH. Final purified peptide: amorphous powder, 140 mg in yield in a synthesis scale of 0.3 mmol. HPLC analysis: tR=20.23 min, purity 99.7%, gradient 10% B to 30% B over 20 min; MS (M+H+): expected molecular ion mass 679.4, observed 679.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09334305B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-3196bf5c95b3480e8ac001ec7904becb |
| Source note | uspto-grants-2016_05 |