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HRID523306

反应详情

EQUATION

反应方程式

HRID 523306 的结构方程式

REACTANTS

反应物

5
结构：CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O
HCID637610

Boc-D-phenylalanine

C14H19NO4

结构：O=C(O)[C@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21
HCID688136

1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}proline

C20H19NO4

结构：O=C(N[C@H](Cc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21
HCID978332

未命名化合物

结构：CCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O
HCID2756111

Fmoc-D-norleucine

C21H23NO4

结构：Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c(C)c2c1OC(C)(C)C2
HCID178427571

未命名化合物

PRODUCTS

生成物

1
结构：CCCC[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)N1CCC[C@@H]1C(=O)O
HCID178445950

未命名化合物

PROCEDURE

实验过程

The compound was prepared according to the procedure described in the synthesis of compound (1). The amino acid derivatives used were Boc-D-Phe-OH, Fmoc-D-Phe-OH, Fmoc-D-Nle-OH, Fmoc-D-Arg(Pbf)-OH, and Fmoc-D-Pro-OH. Final purified peptide: amorphous powder, 140 mg in yield in a synthesis scale of 0.3 mmol. HPLC analysis: tR=20.23 min, purity 99.7%, gradient 10% B to 30% B over 20 min; MS (M+H+): expected molecular ion mass 679.4, observed 679.5.

WORKUP

后处理

  1. customThe compound was prepared
  2. customFinal purified peptide
  3. customamorphous powder, 140 mg in yield in a synthesis scale of 0.3 mmol