2-(Methylthio)-5,6,7,8-tetrahydroquinazolin-4(3H)-one → HCID 178518707, compound

Participants

Reaction Steps

2-Methylsulfanyl-5,6,7,8-tetrahydro-3H-quinazolin-4-one (100 mg; 0.51 mmol) and 6-piperazin-1-ylpyridin-2-ol (91.3 mg; 0.51 mmol) are reacted in isoamyl alcohol (1 ml) in accordance with the procedure for Example 9 and worked up. The crude product obtained after conventional work-up is purified by column chromatography, triturated with diethyl ether, filtered off with suction and dried; yield: 17 mg (10%), crystals;

Provenance & Evidence