HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholin-4-yl-piperazin-1-yl-methanone → HCID 136268346, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholin-4-yl-piperazin-1-yl-methanone | HCID 700139 | — |
| Reactant | 2-(Methylthio)-5,6,7,8-tetrahydroquinazolin-4(3H)-one | HCID 135435256 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Solvent | Isoamyl Alcohol | HCID 31260 | — |
| Product | HCID 136268346 | HCID 136268346 | — |
Reaction Steps
2-Methylsulfanyl-5,6,7,8-tetrahydro-3H-quinazolin-4-one (100 mg; 0.51 mmol) and piperazinocarboxylic acid morpholide (152.3 mg; 0.76 mmol) are reacted in isoamyl alcohol (1.5 ml) in accordance with the procedure for Example 1 (reaction time 8 h) and worked up. The crystals obtained are dissolved in acetonitrile and water and freeze-dried; yield: 38 mg (21%), crystals;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09339503B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-3d1e96a97de24f42a7e1f5b9491026b9 |
| Source note | uspto-grants-2016_05 |