Triethylamine → HCID 136268339, compound

Participants

Reaction Steps

2-Methylsulfanyl-5,6,7,8-tetrahydro-3H-quinazolin-4-one (100 mg; 0.51 mmol), 4-trifluoromethylpiperidine * HCl (97 mg; 0.51 mmol) and triethylamine (141.3 μl; 1.02 mmol) are reacted in isoamyl alcohol (1 ml) in accordance with the procedure for Example 1 (reaction time 4 h) and worked up. The crude product obtained in this way is purified by column chromatography; yield: 43 mg (28%), crystals;

Provenance & Evidence