3-Hydroxypyridine → HCID 66712882, compound

HRID 523769Notes

Reaction equation

HRID 523769 reaction equation
[CH2:1]([O:5][C:6]([C:8]1[N:9]=[C:10](Cl)[C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:7])[CH2:2][CH2:3][CH3:4].[N:20]1[CH:25]=[CH:24][CH:23]=[C:22]([OH:26])[CH:21]=1>>[CH2:1]([O:5][C:6]([C:8]1[N:9]=[C:10]([O:26][C:22]2[CH:21]=[N:20][CH:25]=[CH:24][CH:23]=2)[C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 79713-HydroxypyridineHCID 860145021-Chloro-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester

Product 1

HCID 66712882HCID 66712882, compound

Procedure

Synthesized from 1-chloro-4-hydroxy-isoquinoline-3-carboxylic acid butyl ester and pyridin-3-ol in analogy to Example D-20 d); MS-(+)-ion: M+1=339.1.

Sources & evidence

ORD record
ord-7bbc9708ea8944f8aaf899d74f74dfb7
Source dataset
uspto-grants-2016_05
Patent number
US09339527B2

Reaction notes

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