反应详情

温度

70 °C

To a mixture of thiosemicarbazide (2) (4.55 g, 50.0 mmol) in water (90 mL) was added pyruvic acid (1) (4.40 g, 50.0 mmol). The mixture was heated at 70° C. for 20 min (while a white solid precipitated). After cooling to room temperature, the white solid was collected by filtration, washed with water and dried in air to give 2-(2-carbamothioylhydrazono)propanoic acid (3).

1. customprecipitated)
2. temperatureAfter cooling to room temperature
3. filtrationthe white solid was collected by filtration
4. washwashed with water
5. customdried in air