HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 86669559, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 86669557 | HCID 86669557 | — |
| Solvent | Methanol tetrahydrofuran water | HCID 21892291 | — |
| Product | HCID 86669559 | HCID 86669559 | 73.3% |
Reaction Steps
The compound of example B8 was obtained by similar method described in example B1 using 3-[2-[[2-(6-cyclopentylsulfonyl-3-pyridyl)-2-tetrahydropyran-4-yloxy-acetyl]amino]thiazol-5-yl]oxybenzoic acid methyl ester (Example A10; 0.140 g, 0.232 mmol), LiOH (0.049 g, 1.16 mmol) in Water:THF:MeOH (2:1:0.2 8 mL) to provide the title compound (0.100 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340506B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-7cac5e32f5d947208f46a64751920651 |
| Source note | uspto-grants-2016_05 |