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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 524437Generated: October 30, 2026

Lithium Hydroxide → HCID 86669559, compound

https://huagongshe.com/reaction/524437

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 86669557HCID 86669557—
SolventMethanol tetrahydrofuran waterHCID 21892291—
ProductHCID 86669559HCID 8666955973.3%

Reaction Steps

The compound of example B8 was obtained by similar method described in example B1 using 3-[2-[[2-(6-cyclopentylsulfonyl-3-pyridyl)-2-tetrahydropyran-4-yloxy-acetyl]amino]thiazol-5-yl]oxybenzoic acid methyl ester (Example A10; 0.140 g, 0.232 mmol), LiOH (0.049 g, 1.16 mmol) in Water:THF:MeOH (2:1:0.2 8 mL) to provide the title compound (0.100 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09340506B2
Source datasetuspto-grants-2016_05
ORD IDord-7cac5e32f5d947208f46a64751920651
Source noteuspto-grants-2016_05