Hydrazine hydrate (1:1) → (4-Chloro-phenyl)-(2-hydrazino-9-isobutyl-9H-purin-6-yl)-amine

HRID 524522Notes

Reaction equation

HRID 524522 reaction equation
Cl[C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH2:11][CH:12]([CH3:14])[CH3:13])=[C:4]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)[N:3]=1.O.[NH2:24][NH2:25]>>[Cl:22][C:19]1[CH:20]=[CH:21][C:16]([NH:15][C:4]2[N:3]=[C:2]([NH:24][NH2:25])[N:10]=[C:9]3[C:5]=2[N:6]=[CH:7][N:8]3[CH2:11][CH:12]([CH3:14])[CH3:13])=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 59322268(2-chloro-9-isobutyl-9H-purin-6-yl)(4-chloro-phenyl)-amine

Product 1

HCID 59322257(4-Chloro-phenyl)-(2-hydrazino-9-isobutyl-9H-purin-6-yl)-amine

Procedure

Was prepared according to Example 8 from (2-chloro-9-isobutyl-9H-purin-6-yl)(4-chloro-phenyl)-amine and hydrazine monohydrate.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-442540e1613e4554b991664568319740
Source dataset
uspto-grants-2016_05
Patent number
US09340544B2

Reaction notes

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