HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-benzyl 4-benzyl-2,2-dimethylmorpholine-3-carboxylate → (S)-2,2-dimethylmorpholine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-benzyl 4-benzyl-2,2-dimethylmorpholine-3-carboxylate | HCID 118118262 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (S)-2,2-dimethylmorpholine-3-carboxylic acid | HCID 90043546 | 70% |
Reaction Steps
(S)-benzyl 4-benzyl-2,2-dimethylmorpholine-3-carboxylate (10.4 g, 30.8 mmol) was reacted with H2 by Pd/C catalysis (10%, 1 g) according to the procedure as described in Example 34, Step C to give the title compound as a white solid (3.4 g, 70%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-39aed62d17d74ae187e3564e73db5ae1 |
| Source note | uspto-grants-2016_05 |