Isopropylamine → N-Isopropylmorpholine-3-carboxamide

Participants

Reaction Conditions

Reaction Steps

A mixture of methyl morpholine-3-carboxylate hydrochloride (0.22 g, 1.2 mmol) and propan-2-amine (2.78 g, 47 mmol) was stirred at 60° C. for 12 hours under N2. The mixture was concentrated in vacuo to give the title compound as brownish sticky oil (0.2 g, 95%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence