HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 1-methyl-1H-1,2,4-triazole-3-carboximidamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 1-methyl-1H-1,2,4-triazole-3-carbonitrile | HCID 60710317 | — |
| Product | 1-methyl-1H-1,2,4-triazole-3-carboximidamide hydrochloride | HCID 90044121 | 78.8% |
Reaction Steps
1-methyl-1H-1,2,4-triazole-3-carbonitrile (20 g, 185 mmol) was reacted with sodium methoxide (14 g, 295 mmol) and ammonium chloride (14.8 g, 277.5 mmol) according to the procedure as described in Example 61, Step B to give the title compound as a white solid (23.44 g, 78.8%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-ca98bc871af843d284830ebbfdef4d73 |
| Source note | uspto-grants-2016_05 |