Morpholine-2-carboxylic acid hydrochloride → HCID 73297048, compound

Participants

Reaction Steps

Ethyl 6-(bromomethyl)-4-(2,4-dichlorophenyl)-1,4-dihydro-[2,2′-bipyrimidine]-5-carboxylate (0.72 g, 1.53 mmol) (The compound was synthesized according to the procedure as described in WO2010069147) was reacted with morpholine-2-carboxylic acid hydrochloride (0.26 g, 1.53 mmol) according to the procedure as described in Example 28 to give the title compound as a yellow solid (0.45 g, 56%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence