3-Morpholinecarboxylic acid → HCID 73296880, compound

Participants

Reaction Steps

Ethyl 6-(bromomethyl)-2-(5-chlorothiazol-4-yl)-4-(2,4-dichlorophenyl)-1,4-dihydropyrimidine-5-carboxylate (0.78 g, 1.53 mmol) was reacted with morpholine-3-carboxylic acid (0.2 g, 1.53 mmol) according to the procedure as described in Example 28 to give the title compound as a yellow solid (0.29 g, 34%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence