反应详情

Ethyl 4-(2-bromo-4-fluorophenyl)-6-(bromomethyl)-2-(1-methyl-1H-1,2,4-triazol-3-yl)-1,4-dihydropyrimidine-5-carboxylate (0.5 g, 1 mmol) was reacted with morpholine-3-carboxylic acid hydrochloride (0.17 g, 1 mmol) according to the procedure as described in Example 1, Step C to give the title compound as a yellow solid (0.25 g, 45%). The compound was characterized by the following spectroscopic data: