HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → Ethyl 1-benzyl-4-methylpiperazine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Ethyl 1-benzylpiperazine-2-carboxylate | HCID 10682021 | — |
| Product | Ethyl 1-benzyl-4-methylpiperazine-2-carboxylate | HCID 10563447 | 73% |
Reaction Steps
Ethyl 1-benzylpiperazine-2-carboxylate (3.03 g, 12.2 mmol) was reacted with iodomethane (1.73 g, 12.2 mmol) according to the procedure as described in Example 48, Step A to give the title compound as yellow oil (2.33 g, 73%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-99866f51bb00415ca373b5085a1e30b6 |
| Source note | uspto-grants-2016_05 |