Methylamine hydrochloride → HCID 118107592, compound

Participants

Reaction Steps

3-(4-((6-(2-bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)propanoic acid (0.69 g, 1.19 mmol) was reacted with methanamine hydrochloride (0.12 g, 1.8 mmol) according to the procedure as described in Example 62, Step B to give the title compound as a yellow solid (0.27 g, 38%). The compound was characterized by the following spectroscopic data:

Provenance & Evidence