HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-1,3-thiazol-2-amine → 5-Methoxythiazole-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-1,3-thiazol-2-amine | HCID 20316283 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Product | 5-Methoxythiazole-2-carbonitrile | HCID 90044383 | 30% |
Reaction Steps
5-methoxythiazol-2-amine (2.6 g, 20 mmol) was reacted with CuCN (4 g, 44 mmol) according to the procedure as described in Example 61, Step A to give the title compound as brownish oil (0.84 g, 30%). The compound was characterized by the following spectroscopic data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09340538B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-b60f1450e100498aa2dcb7364c0119c2 |
| Source note | uspto-grants-2016_05 |