HRID525307

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID642851

Diethyl(3-pyridyl)borane

C9H14BN

结构：CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@]2(C)C(OS(=O)(=O)C(F)(F)F)=CC[C@@H]32)C1

HCID10457059

未命名化合物

PRODUCTS

生成物

结构：CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@]2(C)C(c4cccnc4)=CC[C@@H]32)C1

HCID9821849

Abiraterone acetate

C26H33NO2

PROCEDURE

实验过程

The Suzuki reaction between 3β-acetoxyandrosta-5,16-dien-17-yl trifluoromethanesulphonate (II) and diethyl(3-pyridyl)borane affords crude abiraterone acetate which is purified by silica gel chromatography, eluting with a mixture of ethyl ether and petroleum ether, and finally crystallised from hexane.