HRID525582

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID887

Methanol

CH4O

HCID14797

Potassium hydroxide

HKO

结构：CC(C)(C)OC(=O)N1[C@H](CF)[C@@H](c2ccc(-c3ccc(C#N)nc3)cc2)OC1(C)C

HCID86695461

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1[C@H](CF)[C@@H](c2ccc(-c3ccc(C(=O)O)nc3)cc2)OC1(C)C

HCID86695462

未命名化合物

PROCEDURE

实验过程

To the solution of (4S,5R)-5-[4-(6-Cyano-pyridin-3-yl) -phenyl]-4-fluoromethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester (0.3 g, 0.729 mmol) in methanol (3 mL) is added KOH (0.409 g, 7.29 mmol) at room temperature.