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HRID525772

反应详情

EQUATION

反应方程式

HRID 525772 的结构方程式

REACTANTS

反应物

2
结构：Cl.OCC1CNC1
HCID24801400

(Azetidin-3-yl)methanol--hydrogen chloride (1/1)

C4H10ClNO

结构：O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(I)c1
HCID86702626

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC(CO)C2)c(I)c1
HCID89906278

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in an analogous fashion to that described in Stage 88.1 using 6-chloro-N-(4-(chlorodifluoromethoxy)phenyl)-5-iodonicotinamide (Stage 48.3) and 3-azetidinemethanol hydrochloride to afford a beige solid. HPLC (Condition 7) tR=6.5 min, UPLC-MS (Condition 8) tR=1.1 min, m/z=510.0/512.0 [M+H]+.

WORKUP

后处理

  1. customto afford a beige solid