HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,5-Diphenylhydantoin → 3-[(3-Cyanophenyl)methyl]-4,5-dihydro-5,5-diphenyl-1H-imidazol-2,4(3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,5-Diphenylhydantoin | HCID 1775 | — |
| Reactant | Benzonitrile, 3-(bromomethyl)- | HCID 97249 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-[(3-Cyanophenyl)methyl]-4,5-dihydro-5,5-diphenyl-1H-imidazol-2,4(3H)-dione | HCID 18975921 | — |
Reaction Steps
Prepared by reacting 25.5 g (0.101 Mol) of 5,5-diphenylhydantoin with 21.15 g (0.108 Mol) of 3-(bromomethyl)-benzonitrile in the presence of 12.0 g (0.107 Mol) of potassium tert.-butoxide and 200 ml of anhydrous dimethylformamide. After conventional working up 34.0 g (92% of theory) of colourless crystals were obtained, mp. 160°-164° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616620 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-2c4e7f36e9c3472cb708dcb2ea44cdc0 |
| Source note | uspto-grants-1997_04 |