HRID52601

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID74637

2,2-Diphenylacetyl chloride

C14H11ClO

结构：CN(Cc1ccc(O)cc1)C(=O)[C@H](N)CCCNC(N)=N[N+](=O)[O-]

HCID136381118

未命名化合物

PRODUCTS

生成物

结构：CN(Cc1ccc(O)cc1)C(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(c1ccccc1)c1ccccc1

HCID136381117

未命名化合物

收率 85%

PROCEDURE

实验过程

Prepared analogously to Example 69c) from (R)-N5 -[amino(nitroimino)methyl]-N-[(4-hydroxyphenyl)methyl]-N-methyl-ornithinamide and diphenylacetylchloride in a yield of 85% of theory.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-44d88b6047eb4e58b01cfd064ab12ca2
来源数据集: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05616620
来源说明: uspto-grants-1997_04

反应 SMILES

[NH2:1][C:2](=[N:21][N+:22]([O-:24])=[O:23])[NH:3][CH2:4][CH2:5][CH2:6][C@H:7]([C:9]([N:11]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=1)[CH3:12])=[O:10])[NH2:8].[C:25]1([CH:31]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[C:32](Cl)=[O:33])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[NH2:1][C:2](=[N:21][N+:22]([O-:24])=[O:23])[NH:3][CH2:4][CH2:5][CH2:6][C@H:7]([C:9]([N:11]([CH2:13][C:14]1[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=1)[CH3:12])=[O:10])[NH:8][C:32](=[O:33])[CH:31]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1