Hydrochloric Acid → HCID 178483490, compound
Reaction equation
[CH3:1][N:2]([CH3:19])[CH2:3][CH2:4][C@H:5]1[CH2:10][CH2:9][C@H:8]([NH:11]C(=O)OC(C)(C)C)[CH2:7][CH2:6]1.[ClH:20]>>[ClH:20].[ClH:20].[CH3:19][N:2]([CH3:1])[CH2:3][CH2:4][C@H:5]1[CH2:6][CH2:7][C@H:8]([NH2:11])[CH2:9][CH2:10]1Participants
3
Procedure
Following general procedure IV-1, tert-butyl {trans-4-[2-(dimethylamino)ethyl]-cyclohexyl}carbamate (330 mg, 1.2 mmol) was reacted with 6 N HCl (2 mL) to afford the desired product as a viscous colorless oil that was used without purification.
Sources & evidence
- ORD record
- ord-b72f8df7fbb040a59bbabaddc9ae40aa
- Source dataset
- uspto-grants-2016_05
- Patent number
- US09345709B2
Reaction notes
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