6-Methoxy-3-pyridinylamine → HCID 178471947, compound

HRID 526250Notes

Reaction equation

HRID 526250 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][N:4]=1.[CH:10]1([C:14]([C:16](=[CH:22]OCC)[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[O:15])[CH2:13][CH2:12][CH2:11]1>>[CH:10]1([C:14]([C:16](=[CH:22][NH:9][C:6]2[CH:5]=[N:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[O:15])[CH2:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 811216-Methoxy-3-pyridinylamineHCID 117774800HCID 117774800, compound

Product 1

HCID 178471947HCID 178471947, compound

Procedure

Ethyl 2-(cyclobutanecarbonyl)-3-((6-methoxypyridin-3-yl)amino)acrylate was prepared with conditions described in Example 99 using 2-methoxy-5-aminopyridine and ethyl 2-(cyclobutanecarbonyl)-3-ethoxyacrylate.

Sources & evidence

ORD record
ord-1c893d46b5334b33b72b24a92702ea75
Source dataset
uspto-grants-2016_05
Patent number
US09345709B2

Reaction notes

Loading…